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An exploratory study on the use of event-related potentials as an objective measure of auditory processing and therapy effect in patients with tinnitus: A transcranial direct current stimulation study

Otology & Neurotology Sep 19, 2019

Jacquemin L, Mertens G, Van de Heyning P, et al. - In this prospective exploratory study involving 22 chronic tinnitus patients, researchers investigated the value of event-related potentials (ERPs) in the evaluation of high-definition transcranial direct current stimulation (HD-tDCS) for tinnitus treatment. In a study with HD-tDCS in tinnitus patients, the current study was the first to explore ERPs as an objective measure. Adding ERPs to the results of tinnitus studies may lead to a stronger knowledge of future therapeutic effects. The findings showed a shortening of ERP latencies and an increased N2 amplitude, reflecting possibly more efficient sound processing in the auditory cortex with higher recruitment of synchronized neurons. Future studies should elaborate on these results to provide a better insight into the underlying mechanism of changes in ERP after tinnitus treatment by collecting control data and adding a sham group.
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