Denham M, et al. - Researchers examined the influence of using self-fixating mesh during laparoscopic inguinal hernia repair (LIHR) on postoperative quality of life (QoL). They tested their assumption that patients receiving self-fixating mesh during totally extraperitoneal (TEP) LIHR vs those receiving non-fixating mesh will report less pain and improved QoL. In this IRB-approved, single-blinded randomized controlled trial, enrollment of 270 patients was done (137 non-fixating vs 133 self-fixating). In the first 2–3 days, worse postoperative pain was reported in patients receiving self-fixating mesh vs those receiving non-fixating mesh. At 3 weeks or 1 year postoperatively, no differences across QoL metrics (Surgical Outcomes Measurement System and Carolinas Comfort Scale) were evident between the groups. No positive impact on QoL after TEP LIHR was noted in correlation to self-fixating mesh.