Yu WS, et al. - Researchers assessed the prospect of anastomotic leakage following esophageal cancer surgery by measuring amylase levels repeatedly in the fluid from the drainage tube inserted at the cervical anastomotic site. They retrospectively reviewed 99 patients who underwent esophagectomy and cervical esophagogastrostomy. Outcomes suggest a possible value of amylase levels measured in the cervical drain fluid in predicting anastomotic leakage. Both the leakage and non-leakage groups showed an increase in the amylase levels until postoperative day (POD) 2, but the levels then decreased in the non-leakage group, while the levels peaked on POD 3 in the leakage group.