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Amniotic fluid volume at presentation with early preterm prelabor rupture of membranes and association with severe neonatal respiratory morbidity

Ultrasound in Obstetrics & Gynecology Dec 15, 2019

Weiner E, Barrett J, Zaltz A, et al. - In this retrospective study, researchers explored the connection between amniotic fluid volume (AFV) at the time of presentation with early preterm prelabor rupture of membranes (PPROM) and severe neonatal respiratory morbidity and other adverse pregnancy outcomes. The sample consisted of all women with a singleton pregnancy, admitted to a single tertiary referral center between 2004 and 2014, for expectant management of PPROM at 20 + 0 to 28 + 6 weeks' gestation. A total of 580 women were involved, of whom 304 had normal AFV, 161 had oligohydramnios and 115 had severe oligohydramnios at presentation. Data reported that severe respiratory morbidity rates were 16.1%, 26.7% and 45.2%, respectively. In women with early PPROM, AFV is independently associated with severe neonatal respiratory morbidity at present, as measured by the MVP on ultrasound examination. When advising women with early PPROM about the neonatal outcome and management choices, this data may be taken into account.
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