Li Y, WangZ, Boileau I, et al. - As gambling disorder is characterized by impairments in decision-making and reward processing related with dysfunctional brain activity in the orbitofrontal cortex (OFC), researchers assessed if structural abnormalities accompany OFC functional abnormalities in these cases by evaluating the organization of sulci and gyri in the OFC. From nine existing studies, they gathered data on the brain structure of 165 individuals with gambling disorder and 159 healthy controls. As per findings, individuals with gambling disorder display skewed distribution of OFC sulcogyral patterns, with a higher prevalence of Type II pattern vs healthy controls. The results suggest the possible value of pattern Type II as a premorbid structural brain marker of the disease.