Zhou F , et al. - This study was planned to investigate the amplitude of intrinsic low-frequency oscillations (LFOs) in patients with discogenic low-back and leg pain (LBLP). Observations revealed widespread abnormalities in amplitude of low-frequency fluctuations (ALFFs) in the pain matrix and information-processing regions as well as a decrease in ALFF in the default mode network (DMN). Results seemed valuable for improving the knowledge regarding the nature of the link between intrinsic activity and peripheral pain and sensory impairment in discogenic LBLP patients.