Hong S, et al. - Intrinsic functional connectivity patterns were explored in patients with herpes zoster (HZ) and postherpetic neuralgia (PHN). Both HZ and PHN patients demonstrated decreased functional connectivity density in the precuneus, indicating a disrupted default-mode network. Furthermore, hyperconnectivity was observed in systems involved in pain transmission and interpretation in the HZ group (initial stage of the virus infection), but hyperconnectivity only occurred in the hippocampus in the PHN group (neuropathic pain stage).