Oruc Y, Celik F, Ozgur G, et al. - In view of the relationship between oxidative stress and diabetic retinopathy (DRP), researchers sought to determine the levels of the oxidative stress markers 4-hydroxynonenal (4-HNE) and 8-hydroxy-2′-deoxyguanosine (8-OHdG), as well as asprosin, in the blood and aqueous humor (Aq) of patients with and without DRP. The sample consisted of 30 patients with single-eye DRP and cataract (DRP + C), 30 patients with diabetes mellitus and cataract without DRP (DM + C), and 30 healthy control (CON) participants. According to this retrospective study, asprosin, 4-HNE, and 8-OHdG levels were significantly higher in both Aq and blood samples in patients with DRP relative to the group of patients without DRP. Such results indicate that the measurement of asprosin, 4-HNE, and 8-OHdG levels can support clinicians in determining the risk of DRP development.