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All-cause and cause-specific mortality risks associated with alopecia areata: A Korean nationwide population-based study

JAMA Aug 21, 2019

Lee S, et al. - Researchers examined all-cause and cause-specific mortality risk in patients with alopecia areata relative to the risks evident in the general population. They conducted a nationwide population-based cohort study and identified a higher mortality risk associated with intentional self-harm/psychiatric diseases among patients with alopecia areata than controls. Patients with alopecia totalis/universalis also showed increased mortality risk correlated with smoking-associated malignant diseases including lung cancer; however, they showed reduced mortality risk associated with diabetes mellitus. These findings support the possible contribution of the psychiatric burden of alopecia areata to heightened mortality associated with self-harm, psychiatric diseases, and smoking-associated malignant diseases.
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