Baglia ML, et al. - Researchers conducted a population-based case-case study among women aged 20–69 years to determine the link between alcohol, smoking, and risk of human epidermal growth factor receptor 2-overexpressing (H2E) and triple-negative (TN) breast cancer vs estrogen receptor [ER+] breast cancers. As per findings, alcohol is associated with lower risk of H2E breast cancer relative to ER+ breast cancer. This study supports the epidemiologic evidence that breast cancer subtypes differ regarding their etiology.