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Albuminuria and retinal vessel density in diabetes without diabetic retinopathy: The Kailuan Eye Study

Acta Ophthalmologica Jan 27, 2021

Wang Q, Liu L, Jonas JB, et al. - Researchers intended to determine if there is an association between retinal vessel density (VD) and albuminuria in diabetic patients without conventionally defined diabetic retinopathy. The cross‐sectional community‐based Kailuan Diabetic Retinopathy Study involved patients with type 2 diabetes without diabetic retinopathy who partook in the community‐based longitudinal Kailuan study and who had undergone ocular fundus photography, kidney function assessment, and optical coherence tomographic angiography (OCT‐angiography) for the assessment the retinal perfusion density (PD) and retinal VD. The sample consisted of 447 patients (mean age: 60.9 ± 9.7 years). Diabetic patients without diabetic retinopathy reported a drop in OCT‐angiographic retinal vascular measurements in association with systemic parameters suggesting chronic kidney disease after adjusting for systemic and ocular parameters. Optical coherence tomographic‐angiographic retinal microvascular parameters can serve as markers for chronic kidney disease.

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