Hallas HW, et al. - Researchers investigated 367 (89%) of the 411 children from the at-risk Copenhagen Prospective Studies on Asthma in Childhood 2000 (COPSAC2000) birth cohort born to mothers with asthma to explore whether low lung function and bronchial hyperreactivity are inherent traits increasing the risk of developing airway inflammation and asthmatic symptoms. They extensively studied 97 children who developed asthma and 270 children without asthma with longitudinal lung function measurements from age 1 month to 13 years. Findings suggested that the group of children who will develop asthma, display the initiation of low lung function in early childhood. They identify the establishment of the lung function trait prior to the development of airway inflammation and asthma. Furthermore, this trait was not worsened with increased duration of asthma symptoms. They suggest preventive measures undertaken during pregnancy as the most effective, due to the manifestation of airway obstruction and increased bronchial reactivity as early as 1 month of age.