Mady LJ, et al. - Experts measured the effect of air pollutants (particulate matter 2.5 [PM2.5] and black carbon [BC]) on chronic rhinosinusitis (CRS) with nasal polyposis (CRSwNP) and CRS without nasal polyposis (CRSsNP). As per the findings, a correlation of the air pollutants with CRS symptom severity was seen that could be influenced by exposure levels, with a more pronounced impact on CRSsNP patients. This was the first study that showed the possible role of inhalant pollutants in CRS phenotypes, thereby, suggesting a critical knowledge gap in environmental risk factors for disease progression.