Mady LJ, et al. - Researchers sought an estimation of the ramifications of air pollutants (particulate matter 2.5 [PM2.5] and black carbon [BC]) on chronic rhinosinusitis (CRS) with nasal polyposis (CRSwNP) and CRS without nasal polyposis (CRSsNP). An association was brought to light between air pollutants with CRS symptom severity that could be affected by exposure levels, with a more substantial impact on CRSsNP patients. The possible role of inhalant pollutants in CRS phenotypes was illustrated in this study, targeting a crucial knowledge gap in environmental risk factors for disease progression.