Martinez S, Yaffe K, Li Y, et al. - In this cohort study involving 316,351 veterans, researchers intended to determine if there is an association between Agent Orange exposure and incident dementia diagnosis in US veterans of the Vietnam era. The Veterans Health Administration data for this cohort study were collected between October 1, 2001, and September 30, 2015, with up to 14 years of follow-up. Even after accounting for the competing risk of death, demographic variables, and medical and psychiatric comorbidities, veterans with Agent Orange exposure were almost twice as likely to be diagnosed with dementia. Additional studies are required to explore potential mechanisms underlying the link between Agent Orange exposure and dementia.