Riedler KL, et al. – This cross–sectional study was performed to analyze the histologic and biochemical properties of auricular and septal cartilage. A significant decrease in glycosaminoglycans, elastin, cell density, and cell size were reported with age in the auricular and septal cartilage of patients over 55 years of age. In septal cartilage, glycosaminoglycan content declines faster with age than auricular cartilage. These age–related changes probably impact biomechanical properties and tissue viability and thereby had implications for graft choice in functional, aesthetic, and reconstructive nasal surgery.