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Age-related changes in cortical and subcortical structures of healthy adult brains: A surface-based morphometry study

Journal of Magnetic Resonance Imaging Jul 18, 2018

Zheng F, et al. - The connections between age and cerebral structures regarding cortical and subcortical changes were investigated in this cross-cohort research. Participants in the study were 54 healthy adults (28 females) aged 21–71 years. Researchers performed a regression analysis to determine the associations between age and cortical thickness, local gyrification index (LGI), and volumes of subcortical structures. The outcomes comprehensively demonstrated the correlations between age and cerebral structures in multiple brain regions. It aids in identifying normal aging and other age-related neuroradiological disorders.
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