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Age determines response to anti-TNFα treatment in patients with ankylosing spondylitis and is related to TNFα-producing CD8 cells

Clinical Rheumatology Mar 28, 2018

Schramm-Luc A, et al. - This study was conducted to determine age-related differences in cellular functions, which could predict the response to treatment with tumor necrosis factor (TNF) α inhibitors in ankylosing spondylitis (AS) patients. They noted that TNFα-producing CD8 cells could mediate the influence of age on the response to anti-TNFα treatment in AS patients.
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