Legdeur N, et al. - Researchers explored the age dependency of risk factors for cognitive decline in cognitively healthy subjects aged 55-85 years at baseline. Various risk factors had a negative impact on the cognitive decline decreases with higher age. This diminished association at higher age was explained by a combination of epidemiological factors, such as the selection towards healthier subjects during follow-up, but also risk factor specific features, like ensuring the cerebral blood flow in case of hypertension. When applying preventive strategies to avert cognitive decline, taking these age differences into account was important.