Sattar N, et al. - Researchers used the Swedish National Diabetes Registry to examine the link between age at type 2 diabetes mellitus (T2DM) diagnosis, cardiovascular disease (CVD), and mortality risks in patients with vs without T2DM. They examined a cohort of 318,083 patients with T2DM matched with < 1.6 million control participants who were randomly selected from the general population and matched based on age, sex, and county. Total mortality, cardiovascular mortality, non-cardiovascular mortality, coronary heart disease, acute myocardial infarction, stroke, heart failure, and atrial fibrillation were the evaluated outcomes. Compared with controls, the highest excess risk for most outcomes was observed among patients with T2DM diagnosed at ≤ 40 years of age. With each increasing decade at diagnostic age, there was a progressive reduction in all risks. Overall, findings highlighted the prognostic significance of age at diagnosis of T2DM for survival and cardiovascular risks. Preventing/delaying T2DM onset in younger individuals was further supported.