Age‐specific prevalence and determinants of depression in long‐term breast cancer survivors compared to female population controls
Cancer Medicine Oct 13, 2020
Doege D, Thong MSY, Koch‐Gallenkamp L, et al. - The age‐specific prevalence of depressive symptoms was compared between breast cancer (BC) survivors and female population controls, and between disease‐free BC survivors vs BC survivors with self‐reported recurrence vs controls. In addition, factors that determine depression in BC survivors were investigated. German multi‐regional population‐based studies were conducted recruiting about 3,010 BC survivors (stage I‐III, 5‐16 years postdiagnosis), and 1,005 population controls. After adjustment for age and education mild/severe depression was more frequent among BC survivors relative to population controls. Observations suggest a common occurrence of depression in BC survivors and this is even more common after BC recurrence. In lieu of these observations, they recommend clinicians to routinely screen and normalize referral to psychological care. Significant determinants of mild depression in BC survivors were age, income, living independently, recurrence, and BMI, while significant determinants of severe depression were age, education, employment, income, recurrence, and BMI.
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