Jaggi D, Nagamany T, Ebneter A, et al. - In this observational study, researchers reported long-term outcomes on best-corrected visual acuity and treatment intervals with a treat-and-extend regimen in patients with neovascular age-related macular degeneration (nAMD). They involved treatment-naïve patients with nAMD, treated with aflibercept. Participants in the study were 82 patients with a follow-up period of ≥ 2 years. Initial vision gains were maintained with a reasonable treatment burden after 4 years of treatment, even without an initial loading phase. The findings on functional outcomes are similar to large controlled studies.