Demakakos P, et al. - Researchers sought to examine how adverse childhood experiences (ACE) are associated with the risk of miscarriage in the general population via performing a retrospective national cohort study of 2,795 women aged 55–89 years from the English Longitudinal Study of Ageing (ELSA). At least one miscarriage was reported in 553 women (19.8% of the sample) during their lifetime. After adjusting for birth cohort, age at menarche and childhood socioeconomic position, women with ≥ 3 ACE were noted to be two times more likely to experience a single miscarriage in their lifetime and more than three times more likely to experience recurrent miscarriages (≥2 miscarriages) when compared with women with no ACE. They noted individual association of childhood experiences of physical and sexual abuse with raised risk of miscarriage. Outcomes thereby suggest correlation of specific ACE as well as the summary ACE score with an elevated risk of single and recurrent miscarriages.