Lanier P, et al. - Authors aim to further the work exploring adverse childhood experiences (ACEs) by proposing a novel approach to understanding the impact of ACEs through applying advanced analytical methods to examine whether combinations of ACEs differentially impact child health outcomes. In this work, different combinations of ACEs seem to carry different risk for child health. For improving child health, interventions tailored to specific ACEs and ACE combinations may have a greater effect. High risk for poor health outcomes is observed particularly among children experiencing specific ACE combinations (e.g., poverty and parental mental illness). Therefore, they recommend clinicians routinely assess for ACEs to identify children exposed to the most problematic ACE combinations and once identified, give priority to these children for supportive interventions tailored to their specific ACE exposure and needs.