Mansuri F, et al. - In this cross-sectional study, researchers investigated if and how ACEs associate with the history of frequent headaches (including migraine) among children 3-17 years old using data from the 2016 and 2017 US National Survey of Children’s Health. Abuse (physical, emotional, or sexual), parental divorce, death, mental illness, or addiction are included as ACEs and are linked with higher morbidity and mortality in adulthood. They assessed a total of 61,656 children; of these, 26,884 (48.6%) experienced at least 1 ACE and 3,426 (6.5%) experienced 4+ ACEs. They observed headaches more frequently in children experiencing one or more ACEs vs none. In line with other studies, this work supports the earlier initiation of the adverse ACE-related health outcomes than previously acknowledged. Additionally, struggling due to low income may render a constellation of chronic stressors that individually add to poor health outcomes in childhood as compared with other individual ACEs.