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Advanced stage at diagnosis and elevated mortality among US patients with cancer infected with HIV in the National Cancer Data Base

Cancer May 09, 2019

Coghill AE, et al. - Using data from the National Cancer Data Base (2004-2014), researchers investigated the impact of HIV on the rate of progression to advanced cancer or mortality. They identified 14,453 people living with HIV (PLWH) and 6,368,126 HIV-uninfected patients diagnosed with cancers of the oral cavity, stomach, colorectum, anus, liver, pancreas, lung, female breast, cervix, prostate, bladder, kidney, and thyroid and melanoma. Both groups were compared for stage of disease at the time of presentation and mortality after diagnosis. They found that the likelihood of being uninsured was higher in HIV-infected patients with cancer; these patients also had less chances to have private health insurance. Even after accounting for health care-related factors, the probability of being diagnosed with advanced-stage cancers and to have elevated mortality following a cancer diagnosis was higher in PLWH.

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