• Profile
Close

Adult height after gonadotropin‐releasing hormone agonist treatment in girls with early puberty: A meta‐analysis

Clinical Endocrinology May 15, 2020

Park HK, et al. - In this analysis of previously published reports, researchers investigated the impacts of gonadotropin‐releasing hormone (GnRH) agonist treatment on adult height and the factors correlated with adult height outcomes. In total, 14 studies identified from a search of electronic databases (AMED, EMBASE, MEDLINE and RISS) have been involved. Controlled studies of girls who developed puberty before 10 years of age and measurements of adult heights of individuals were chosen. Studies using only long‐acting GnRH agonists to suppress puberty have been involved. The mean age of the individuals ranged from 6.3 to 9.0 years. The meta‐analysis exhibited a pooled mean difference in adult height of 3.2 cm and a 95% confidence interval of 1.3 to 5.1 cm. The disparity in height between the treated subjects and controls was significantly correlated with treatment duration rather than age at treatment start or discrepancy between bone age and chronological age.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay