Gaujoux S, Hain E, Marcellin L, et al. - Maternal and fetal outcomes after adrenalectomy during pregnancy were investigated. Researchers identified a total of 12 women who underwent adrenalectomy at a median gestation of 20 weeks from January 2003 to July 2018. Among these women, 11 had hyper-secreting lesions, including 8 with cortisol oversecretion, and 11 had benign lesions, including cortisol-secreting adenoma ( n = 5), pheochromocytoma ( n = 2), primary pigmented, nodular adrenal disease ( n = 1), severe Cushing’s disease ( n = 2), and hematoma ( n = 1). Bilateral adrenalectomy was performed on a total of 3 patients with severe Cushing’s disease ( n = 2) and primary pigmented, nodular adrenal disease ( n = 1). This study support feasibility of undertaking a lateral laparoscopic transabdominal approach during pregnancy. Acceptable outcomes were reported for mothers but the underlying disease was identified determining the fetal outcome, with a worse outcome when the adrenalectomy is suggested for malignant lesions or Cushing’s syndrome.