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Adolescent use of combined hormonal contraception and peak bone mineral density accrual: A meta-analysis of international prospective controlled studies

Clinical Endocrinology Feb 14, 2019

Goshtasebi A, et al. - Since many women use combined hormonal contraceptives (CHC) during adolescence during which they are accruing peak areal bone mineral density (BMD) that relates to lifetime fracture risk, researchers compared peak BMD accrual in adolescents using and not using CHC. According to findings, the accrual of spinal bone mineral density in adolescent women who first took combined hormonal contraceptives vs those who did not use them is significantly lower. These outcomes are relevant to public health because, as in the past, a higher percentage of women begin CHC in adolescence than in early adulthood.
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