Adolescent overweight and obesity and the risk for pancreatic cancer among men and women: A nationwide study of 1.79 million Israeli adolescents
Cancer Nov 16, 2018
Levi Z, et al. – Given the growing concern on the effect of adolescent obesity on adult health, researchers examined the incidence of pancreatic cancer during adulthood in relation to body mass index (BMI) in late adolescence in a cohort of 1087,358 Israeli Jewish men and 707,212 Jewish women. These participants had a compulsory physical examination between ages 16 and 19 years from 1967-2002. Using linkage to the national cancer registry, pancreatic cancer incidence through December 31, 2012 was identified. In accordance with the US Centers for Disease Control and Prevention (CDC) BMI percentiles at baseline, they estimated hazard ratios for pancreatic cancer using multivariable-adjusted Cox regression. Overall, they observed an increased risk for subsequent pancreatic cancer in men and women who were obese or overweight as adolescents.
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