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Adjuvant use of laser in eyes with macular retinoblastoma treated with primary intravenous chemotherapy

British Journal of Ophthalmology Sep 18, 2020

Stacey AW, Tsukikawa M, Fabian ID, et al. - Given that adjuvant use of a laser with systemic chemotherapy for treatment of retinoblastoma may reduce recurrence rates while also causing local side effects, researchers conducted this retrospective review to analyze the effect of laser on visual outcomes. This investigation was carried out at two retinoblastoma centres in the United Kingdom. Patients have considered if at least one eye had a macular tumour. Participants in the study were 76 patients (91 eyes). Systemic chemotherapy alone was used in 71 eyes whereas chemotherapy plus laser was used in 20 eyes. An adjuvant laser is effective in the treatment of retinoblastoma and does not result in increased vitreous recurrence rates. Final visual acuity is determined by the presence of the fovea tumour and not by the use of laser.

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