Ma SJ, et al. - In this analysis of the National Cancer Database (NCDB), researchers assessed the clinical outcomes for resected pancreatic cancer with postoperative chemotherapy followed by concurrent chemoradiation (C + CRT) vs concurrent chemoradiation (CRT) alone or adjuvant chemotherapy alone (C). For analysis, 5,667 patients with resected clinical stage I-II, T1-3N0-1M0 pancreatic adenocarcinoma were identified. It was noted that the majority of patients had pathologic T3N1 pancreatic head adenocarcinoma with negative surgical margins. This NCDB study shows an overall survival (OS) benefit for C + CRT vs C or CRT alone after surgical resection of pancreatic cancer, especially for patients with pathologically positive lymph nodes.