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Adjuvant chemoradiotherapy with epirubicin, cisplatin, and fluorouracil compared with adjuvant chemoradiotherapy with fluorouracil and leucovorin after curative resection of gastric cancer

Journal of Clinical Oncology Nov 23, 2017

Fuchs CS et al. -After curative resection of gastric or gastroesophageal junction adenocarcinoma, increased survival occurred in patients who received post-operative chemoradiotherapy with bolus fluorouracil and leucovorin compared with surgery alone. In the current study, post-operative chemoradiotherapy using a multiagent regimen of epirubicin, cisplatin, and fluorouracil before and after radiotherapy does not improve survival compared with standard fluorouracil and leucovorin before and after radiotherapy after a curative resection of gastric or gastroesophageal junction adenocarcinoma,.

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