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Adjunctive serial post-operative intravitreal methotrexate injections in the management of advanced proliferative vitreoretinopathy

Graefe's Archive for Clinical and Experimental Ophthalmology Apr 29, 2021

Roca JA, Yon-Mendoza A, Huamán N, et al. - Researchers conducted the study for analyzing the impacts of weekly postoperative intravitreal methotrexate injections on eyes with grade C proliferative vitreoretinopathy (PVR) that underwent surgical repair. It was a retrospective case-control study of 16 eyes with retinal detachment and grade C PVR. Seven eyes got weekly intravitreal MTX injections postoperatively as an adjunct, while 9 eyes served as control. For the management of PVR, serial intravitreal MTX as an adjunct to surgical repair holds promise. There was no evidence of corneal epitheliopathy.

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