Shvartzman Y, et al. - This trial was formulated in order to compare the rehospitalization rates of patients with bipolar disorder (BD)-I depressive episode who were discharged with mood stabilizers (MSs) and/or atypical antipsychotics (AAPs) with or without adjunctive antidepressants (ADs). Data unveiled a lower rate of and a longer time to rehospitalization due to adjunctive-AD therapy to MS/AAP at discharge from BD-I depressive episode hospitalization during a 1-year follow up period.