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Adiposity, history of diabetes, and risk of pancreatic cancer in postmenopausal women

Annals of Epidemiology Sep 28, 2018

Kabat GC, et al. - In a large cohort of postmenopausal women, researchers investigated the association of type 2 diabetes mellitus (T2DM) and anthropometric variables with pancreatic cancer risk. A total of 1,054 eligible cases of pancreatic cancer were diagnosed among 158,298 women over a median of 18 years. For the entire cohort, measured body mass index (BMI), waist circumference, waist-to-hip ratio, and self-reported history of diabetes were available; self-reported BMI earlier in life was available on approximately half of the cohort. Findings showed that history of T2DM was associated with increased pancreatic cancer risk, and general and central adiposity were weak risk factors.

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