Ebert T, Gebhardt C, Scholz M, et al. - Researchers examined whether seven circulating adipocytokines (ie, adiponectin, adipocyte fatty acid-binding protein, chemerin, leptin, Pro-Enkephalin, progranulin, and Pro-Neurotensin) are correlated with gestational diabetes mellitus (GDM) or they differ by metabolic and weight changes during pregnancy itself. They assessed a cross-sectional cohort of 222 women comprising of the following three groups matched for age and BMI: (i) 74 pregnant women with GDM; (ii) 74 pregnant women without GDM; and (iii) 74 non-pregnant and healthy women. Dysregulation of five out of seven adipocytokines was observed between pregnant and non-pregnant women, ie, adiponectin, chemerin, leptin, Pro-Enkephalin, and progranulin. Per observation, the seven investigated adipocytokines in discrimination analyses can distinguish pregnancy status but not presence of GDM.