Castro GS, Aguilar-Alvarado CM, Zúñiga-Ramírez C, et al. - For improving medication adherence in patients with Parkinson disease (PD) (the population studied in this research), the likely key requisites include educational strategies, greater involvement of PD patients in decision-making, and consideration of their beliefs and values.

• This is a multicenter, cross-sectional, exploratory study of 800 PD patients from six Latin-American countries.

• By patients, 58.25% of the population showed nonadherence to treatment.

• Forgetfulness and correct timing of doses were the most frequent problems.

• The following were noted in the nonadherent population: a significantly higher proportion of unemployment, free access to medication, troublesome dyskinesias and off-periods, lesser years of education, and worse motor, cognitive, and mood scores.

• Significant contributors to adherence measures were: MDS-UPDRS Part III, Beck Depression Inventory-II, gender, free access to medication, treatment with dopamine agonists alone, years of education, excessive concerns regarding adverse effects, and beliefs concerning being well-treated.