Vallée A, et al. - In the present study, researchers evaluated the added value that spectroscopy can deliver to perfusion utilizing optimal combined classifiers that have the highest differential diagnostic performance to discriminate lymphomas, glioblastomas, and metastases. For this investigation, 55 consecutive subjects with histopathologically proved lymphomas, glioblastomas, and metastases were involved after undergoing MR imaging from January 2013 to January 2016. Findings revealed that spectroscopy offered an added performance value to perfusion using optimal combined classifiers of these modalities, which significantly increased the differential diagnostic performances for these brain tumors.