Kazerooni AF, et al. - Aim of this study was to propose an objective diagnostic method devised based on spatial features for predicting benignity/malignancy of adnexal masses in apparent diffusion coefficient (ADC) maps. In this study, the spatial quantification methodology proposed, which works based on cellular distributions within apparent diffusion coefficient maps of adnexal masses, may serve a helpful computer-aided strategy for objective characterization of adnexal masses.