Acute kidney injury in trauma patients admitted to the ICU: A systematic review and meta-analysis
Intensive Care Medicine Feb 11, 2019
Søvik S, et al. - Via a systematic review and meta-analysis, researchers examined acute kidney injury (AKI) in trauma patients admitted to the intensive care unit (ICU). They collected data on the incidence of AKI, risk factors, renal replacement therapy (RRT), renal recovery, length of stay (LOS), and mortality. Including 24 observational studies comprising 25,182 patients, they identified AKI in 24% of trauma patients admitted to the ICU, with an RRT use among these of 10%. For AKI, risk factors comprised African American descent, high age, chronic hypertension, diabetes mellitus, high Injury Severity Score, abdominal injury, shock, low Glasgow Coma Scale (GCS) score, high APACHE II score, and sepsis. Increased LOS and mortality were observed in correlation with the presence of AKI, however, AKI survivors showed good renal recovery.
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