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Acute kidney injury in critically ill patients after oncological surgery: Risk factors and 1‐year mortality

Nephrology Aug 28, 2021

Córdova-Sánchez BM, Joffre-Torres A, Joachín-Sánchez E, et al. - The independent risk factors for acute kidney injury (AKI) following oncological surgery could include abdominal radiotherapy and abdominal surgical packing in addition to the conventional risk factors.

  • A retrospective single centre study with 434 adult patients admitted to ICU post-oncological surgery.

  • AKI was classified using the Kidney Disease: Improving Global Outcomes criteria.

  • AKI occurred in 61% of patients (n = 264).

  • An independent link of previous abdominal radiotherapy and abdominal surgical packing with stage 2 and 3 AKI was found, with adjusted odds ratio (OR) of 2.6 and OR of 2.6, respectively.

  • Glomerular filtration rate (eGFR) <60 mL/min/1.73m 2 (OR 3.6), abdominal surgery 2.6, intraoperative diuresis <1 mL/k/h (OR 2.4), sepsis (OR 2.5) and mechanical ventilation at ICU admission (OR 7.7) were other independent risk factors.

  • An independent link of both stage 2 and stage 3 AKI with 1-year mortality existed, with adjusted HR of 2.6 and HR of 5.0, respectively.

  • Lower eGFR at 1-year follow-up was seen in cases with postsurgical AKI.

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