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Acute kidney injury in cardiogenic shock: Definitions, incidence, haemodynamic alterations, and mortality

European Journal of Heart Failure Oct 04, 2017

Tarvasmaki T, et al. - This study was performed in patients with cardiogenic shock to determine the incidence, haemodynamic alterations and 90-day mortality of acute kidney injury (AKI) in these subjects and to examine the utility of creatinine, urine output (UO) and cystatin C (CysC) definitions of AKI in prognostication. A frequent incidence of AKI was reported in patients with cardiogenic shock and especially creatinine-based AKI (AKIcrea) predicted poor outcome. In addition, the KDIGO UO criterion seemed rather liberal and, as a predictor of mortality risk, a stricter AKI definition of UO <0.3 mL/kg/h for at least 6 h seemed more useful. Data also reported an association between AKI and haemodynamic alterations reflecting venous congestion and hypoperfusion.
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