Wallin E, et al. - Given the high prognostic accuracy of magnetic resonance imaging (MRI) of the brain including diffusion-weighted imaging (DWI) in unconscious post-cardiac arrest (CA) patients, researchers herein focused on acute MRI findings in the brain in both conscious and unconscious post-CA patients treated with target temperature management (TTM) at 32–34°C for 24 h as well as the relation to patients’ neurological outcome after 6 months. Poor outcome had associations with extensive acute hypoxic/ischemic MRI lesions in the cortical regions, deep gray matter and cerebellum detected by visual analysis as well as low apparent diffusion coefficient values from quantitative measurements. Minor hypoxic/ischemic changes, mainly in the frontal and parietal lobes, were apparent in patients with good outcome.