Schioppo T, et al. - Experts assessed the acute and chronic impacts of 2 different iloprost (ILO) regimens by power Doppler US (PDUS) and nailfold videocapillaroscopy in systemic sclerosis (SSc) patients. They included SSc patients and stratified according to ILO treatment as (group A) no ILO, (group B) ILO once monthly and (group C) ILO for 5 consecutive days. Findings suggested that especially in group B, ILO had an acute effect, as assessed by PDUS. On the contrary, in both treatment groups, an ILO chronic effect was not detectable before the following infusion.