MacMahon H, et al. - Using a subset of size-matched nodules from the National Lung Screening Trial (NLST), researchers compared the accuracy of the Vancouver Lung Cancer Risk Prediction Model to that of trainee and experienced radiologists in predicting the risk of cancer. From the NLST database, 100 cases were identified (size range, 4-20 mm), comprising 20 proven cancers and 80 size-matched benign nodules. The chances of cancer in each case were estimated first independently by 3 experienced thoracic radiologists and 3 trainee radiologists, and thereafter with knowledge of the model’s risk prediction. The cancer risk was better predicted by experienced and trainee radiologists vs the Vancouver model, and no improved accuracy was obtained with the use of the model.