Ebell MH, et al. - Researchers estimated the sensitivity and specificity of signs and symptoms for the diagnosis of acute rhinosinusitis (ARS) by analyzing 17 studies of outpatients with clinically suspected ARS identified from Medline. Any valid reference standard was used to diagnose acute rhinosinusitis, whereas purulence on antral puncture or positive bacterial culture was used to diagnose acute bacterial rhinosinusitis (ABRS). ABRS was detected in nearly one-third of patients with clinically suspected ARS. ABRS was best predicted by overall clinical impression, cacosmia, and pain in the teeth.