Liu J, Qing H, Luo H, et al. - An anthropomorphic chest phantom with 11 pulmonary nodules (six solid nodules and five ground-glass opacities) was scanned using 256-slice multidetector CT scanner at different tube voltage and current (combinations of 80, 100 and 120 kV with 10 to 30 mAs) in order to investigate the exposure parameters with minimized radiation dose for specific pulmonary nodule volumetry using low-dose CT (LDCT). For accurate pulmonary nodule volumetry, the exposure parameters with minimized radiation dose were discovered at 100 kV with 10 mAs along with the predicted impact radiation dose was as low as 0.2 mSv, implying the utility of additionally decreasing radiation dose by reducing tube voltage and current in LDCT lung screening.