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Accuracy of 3-T MRI for preoperative T staging of esophageal cancer after neoadjuvant chemotherapy, with histopathologic correlation

American Journal of Roentgenology Mar 28, 2019

Wang Z, et al. - In this prospective study with histopathologic confirmation, researchers investigated the ability of 3-T MRI to evaluate preoperative T staging of esophageal cancer (EC) treated with neoadjuvant chemotherapy (NAC). For this investigation, they recruited patients who showed EC via endoscopic biopsy and showed stage cT1N+M0 or cT2–T4aN0–N3M0 via pretreatment CT. All subjects in this analysis received two cycles of NAC (paclitaxel and nedaplatin protocol) followed by 3-T MRI and surgical resection. There were 79 patients in the study. According to findings, high-resolution delayed phase StarVIBE had the highest diagnostic accuracy for all T categories except T3 in staging EC after NAC, for which T2-weighted turbo spin-echo (TSE) BLADE had the highest accuracy. The combination of all three sequences did not improve the accuracy of diagnosis.

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