Dai Y, Bolch C, Jung A, et al. - Researchers conducted a retrospective analysis based on a database that archives technical logs of all total knee arthroplastis (TKAs) performed using a computer-assisted orthopedic surgery (CAOS) system to evaluate resection accuracy across the entire TKA application history of a modern CAOS system considering multiple factors. They evaluated coronal resection errors and percentage of outliers (<2° alignment error) in the proximal tibia and distal femur. Multilevel modeling to applied understand if and where the resection error variability was located in the grouping categories, which included geographic region, individual established surgeon, preoperative alignment, adoption phase (learning/proficient), and version of the CAOS software application. This study recruited a sum of 10,144 cases.  Advanced analyses was used to evaluate alignment outcome in TKA bony resection alignment across the history of a specific CAOS system. The evidence revealed high resection alignment accuracy insensitive to geographic region, CAOS software application, adoption phase, preoperative alignment, and inter-surgeon differences.